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Description
Obesity and Type 2 diabetes represent global health challenges, and there is an unmet need for long-lasting and effective pharmacotherapies
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Conversely, additional diagnoses of hypertension or high cholesterol did not increase GLP-1 initiation rates

Recently, agonists of glucagon-like peptide-1 (GLP-1) receptor, designed based on the gut hormone GLP-1, have been developed as anti-obesity drugs and have demonstrated remarkable efficacy in treating both obesity and diabetes
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Clostridium butyricum produces the postbiotic butyrate which stimulates GLP-1. Bifidobacterium infantis produces the postbiotic acetate, and interacts with Akkermansia and Butyricum to promote an ecosystem in the gut that naturally boosts GLP-1
