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It is important to distinguish between the absence of a pharmacological interaction and the potential for coffee to exacerbate certain side effects

GLP-1 RA, GLP-1 receptor agonists

(2014) doi:10.1007/s00109-014-1170-1
Semaglutide is a medication that helps people with type 2 diabetes manage their blood sugar levels effectively
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Patients on both medications may experience larger blood sugar swings and require dose adjustments to either medication or increased monitoring of glucose levels