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A meta-analysis shows that individuals with systolic blood pressure of 140 mmHg or higher or diastolic blood pressure of 80 mmHg or higher in middle age have a 37% increased risk of dementia later in life

For the pairwise comparison of semaglutide OW versus SGLT2i cohorts, IPTW was used to adjust for imbalances in selected baseline patient characteristics between the treatment cohorts

In the CNS, GLP-1 also exert neuroprotective and neurotropic effects by binding to GLP-1R (116)

2124 March 2025

doi: 10.1038/S41598-021-96418-0