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In these trials, adults without diabetes achieved an average weight loss of 14.9% to 17.4% over 68 weeks (NEJM)

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GLP-1 medications are revolutionizing the way we treat type 2 diabetes and obesity

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Alharby H., Abdelati T., Rizk M., Youssef E., Gaber N., Moghazy K

However, the reduction of HDAC6 expression was significantly attenuated by 1 h pretreatment with GLP-1

The recently introduced peptides GLP1/GIP medication can be administered once weekly and have demonstrated substantially improved weight-losing effects within a tolerable safety margin in a series of STEP and SURPASS trials
