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Description
SURMOUNT-4 Investigators
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Many adults in Auburn, MA, struggle with slow metabolism, stubborn fat, and the constant cycle of yo-yo dieting despite consistent efforts with food and exercise

Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers

Without it, no amount of creatine or protein will fully prevent muscle loss during significant caloric restriction

Increasing the dose too quickly may make nausea, vomiting, constipation, diarrhea, reflux, and abdominal discomfort more difficult to manage
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2026 May 25;68(1755):81-3 doi:10.58347/tml.2026.1755a Foundayo (orforglipron) tablets prescribing information