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CD36 is considered a biomarker for atherosclerotic lesion progression since it stimulates inflammatory response and foam cell formation

Understanding these factors helps clinicians identify patients who may require closer monitoring when initiating treatment

They have side effects ranging from nausea and vomiting to diarrhoea and constipation

Dose-dependent increases in heart rate were also observed, consistent with the glucagon receptor agonism component of the drug, and this warrants careful monitoring in individuals with pre-existing cardiac conditions