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Description

These data support the use of lower, better-tolerated doses of GLP-1RAs to treat HFpEF, potentially benefiting a wider range of patients, including those who are not obese or who suffer from side effects with current GLP-1 regimens

GLP-1 plays an important role in regulating appetite by creating the sensation of feeling full after a meal

These may include improvements in endothelial function, reduction in inflammation, and beneficial changes in lipid metabolism

This narrative reviewaims to analyzecurrent findings on the beneficial and adverse ocular effects of GLP-1RAsuse, highlighting studies that elucidate the harmful causes, such as retinal microvascular dysregulation, inflammatory modulation, oxidative stress,osmotic dysregulation from sorbitol accumulation,and metabolic shifts