retatrutide phase 2 obesity nejm 2023 jastreboff for Obesity: Weight-Loss Data Retatrutide is getting attention —

Some weight loss medications raise concerns about lean mass reduction

Abstract GLP-1 receptor agonists represent a breakthrough for managing type-2 diabetes and obesity, offering metabolic benefits across multiple organ systems

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Electrolyte-rich meal planning on GLP-1 medications Supplements are important, but food remains the best source of electrolytes

Signs of an allergic (hypersensitivity) reaction, including rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing

Other Benefits Significant weight loss Appetite suppression Slows digestion Improves insulin sensitivity Dual mechanism (GLP-1 & GIP agonist) Supports metabolic health Reduces risk of obesity-related conditions Non-surgical solution Convenient & easy to use Possible Side Effects Nausea Vomiting Diarrhea Constipation Abdominal discomfort Decreased appetite Fatigue Dizziness Injection site reactions Low blood sugar (especially in diabetics) Other drugs used for weight loss: Naltrexone HCl and Bupropion (Contrave) Contrave (also called naltrexone HCL or bupropion HCL) is made up of two medications: naltrexone HCL and bupropion HCL