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The weight loss market is undergoing a seismic shift as the focus moves from injectable peptides to oral small molecule GLP-1 receptor agonists, led by Eli Lillys promising candidate, orforglipron
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GLP-1 medications may help colon cancer patients live longer by reducing inflammation and improving metabolic health, UC San Diego researchers found in a 6,800-patient study.

Key milestones highlighted in this timeline: 1999 Orlistat (Xenical) The first long-term FDA-approved anti-obesity medication of the modern era
