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They might see a two- to four-pound drop by the end of week four, though some people see more and some see less

Clinical trials demonstrate average weight reductions of approximately 15% with semaglutide 2.4 mg (STEP 1 trial) and 20-22.5% with tirzepatide 10-15 mg (SURMOUNT-1 trial) over 68-72 weeks

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