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Sustained treatment adherence and lifestyle changes are critical for maintaining results with either medication

Metformin should not be used in patients with metabolic acidosis

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Ongoing refills require a clinical follow-up around week 8, which keeps a licensed provider actively monitoring progress rather than auto-renewing indefinitely

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Patel RB, Ter Maaten JM, Ferreira JP, McCausland FR, Shah SJ, Rossignol P, Solomon SD, Vaduganathan M, Packer M, Thompson A, Stockbridge N, Zannad F

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