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How semaglutide works: the GLP-1 single agonist Semaglutide activates one receptor: the glucagon-like peptide-1 (GLP-1) receptor

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This is relevant, as elevated waist circumference is associated with increased metabolically active visceral adipose tissue (VAT) [60], and during medical weight reduction, greater decreases in waist circumference are associated with greater improvements in cardiometabolic risk factors [61]

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