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doi: 10.1172/JCI83349

and (d) functioning through potassium channel-dependent mechanisms, as vasodilation is diminished by K + channel blockade and the removal of endothelial cells (Fig

The reduced expression of vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) by GLP-1 agonists decreases monocyte attachment to endothelial cells, thus preventing the initial process of atherogenesis in ApoE-knockout mice [9,24]

Efficacy and safety of glucagon-like peptide-1/glucagon receptor co-agonist JNJ-64565111 in individuals with type 2 diabetes mellitus and obesity: a randomized dose-ranging study