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The oral formulation comes with specific requirements

The SUSTAIN-6 trial showed reduced risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease

10.1038/s41573-021-00337-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Peng H., Zhang C., Wang M., Zhang W., Xu B., Yan X., et al

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Improved Glucose Homeostasis By enhancing insulin release only in hyperglycemia, they avoid dangerous hypoglycemia while controlling post-meal blood sugar spikes

Individuals with certain skin conditions, like eczema, psoriasis, dermatitis, or severe scarring, might be recommended by their healthcare professional to avoid transdermal patches as their skin condition may worsen or influence drug delivery