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For clinicians, it underscores the need for integrated care models that link metabolic and liver health

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In the meantime, the evidence supports a straightforward approach: start low, escalate slowly, monitor regularly, and evaluate heart rate changes in the context of overall cardiovascular health rather than as an isolated number

For patients with clinical obesity, type 2 diabetes, or cardiovascular risk that requires rapid medical intervention, they remain one of the most effective tools available

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