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glp-1 for ckd Renal effects of receptor agonists and tirzepatide in individuals with type 2 diabetes: seeds of a promising future | Endocrine GLP-1 Medications & Their Potential
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If you are getting more tired as time goes on, especially after the initial adjustment period, electrolyte depletion is a likely culprit

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Hypoglycemia, while less common with tirzepatide alone due to its glucose-dependent mechanism, may occur, particularly in patients taking concurrent medications that affect blood glucose

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Protein and resistance training