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11 There is little risk of hypoglycaemia with these medicines without concomitant use of sulfonylureas or insulin

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Risk vs

(9) Bone resorption is accomplished through the enzymatic activity of osteoclasts

[2] [10] The choice often depends on patient-specific factors: SGLT2 inhibitors are oral and may be preferred by those averse to injections, whilst GLP-1 receptor agonists may produce greater weight loss and are particularly valuable in established cardiovascular disease