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On the other hand, GIP-green-fluoresent-protein (GFP)-knock-in (GIP gfp/+ ) mice, in which GIP secretion is attenuated to half that of WT mice, exhibit no decrease in bone mass compared to wild-type mice, with no significant difference in blood glucose or insulin levels during OGTT after 8 weeks of HFD, although slight glucose intolerance was observed under a normal diet [18, 100]

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While supplements and OTC remedies can help significantly, exercise provides a unique mechanical stimulus to the gut that supplements cannot replicate

Before and after each medication thoracic fluid index and plasma renin, aldosterone and ANP were also assessed

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