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More than 200 million people take it every single day

Ethics II , 710 (2001)

In the PIONEER 3 head-to-head trial, Rybelsus 14 mg delivered an HbA1c reduction of approximately -1.3% versus -0.8% for Januvia at 26 weeks a significantly greater reduction

Research protocols occasionally explore alternate-day administration, but the daily 2 mg dose remains the best-characterized schedule in peer-reviewed literature