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adults were taking GLP-1 medications as of November to lose weight or treat a chronic condition like diabetes, according to a study by the Kaiser Family Foundation

Unfortunately, such a clinical trial has not yet been performed

For instance, in October 2024, a retrospective cohort study indicated that women with type 2 diabetes who used GLP-1 receptor agonists had a lower risk of developing new-onset uterine fibroids compared to those taking other antidiabetic drugs

Patient stratification probably matters more than any single drug choice, because the variable results likely conceal responder subgroups

The history of medical therapy in obesity has been frustrating: many treatments were not effective at all

Discussion GPCR peptide ligands have always been noted for their selectivity, potency and rapid optimization, however, typically peptides are chemically synthesized which is a low-throughput process that intrinsically lacks diversity