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This article traces that evolution, explains exactly how these drugs work inside the pancreas, gut, and brain, and offers a clear rundown of every GLP-1 option on the marketand in the pipelineso you can make informed, evidence-based decisions for metabolic health

Meier JJ, Gethmann A, Gtze O, Gallwitz B, Holst JJ, Schmidt WE, Nauck MA

You need to discard the pen after using it as they are single-use only

GLP-1 agonists also stimulate pancreatic beta cells to secrete insulin and tamp down glucagon secretion from the pancreatic alpha cells

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You are not a candidate for GLP-1 medications if you have: A personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN2) A history of pancreatitis or severe gallbladder disease Active pregnancy or are breastfeeding Type 1 diabetes (without specific provider guidance) Severe gastrointestinal disorders, certain eating disorder histories, and a few other conditions may also disqualify you