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Description
Preclinical proof of concept of enhanced body weight lowering relative to GLP-1 mono-therapy without impaired glycemic control was first demonstrated by two independent research efforts
However, its cutting-edge triple-agonist design comes with a clear financial reality: it is currently the most expensive metabolic compound to synthesize and study

Ma Q, Fu Y, Cao Z, Shao D, Song J, Sheng H, et al

What GLP-1 Is and How Your Body Produces It Naturally GLP-1 is a 30-amino acid peptide hormone secreted by intestinal L-cells in response to nutrient ingestion, particularly glucose and amino acids

The numerous beneficial effects of GLP-1 render this hormone an interesting candidate for the development of pharmacotherapies to treat obesity, diabetes, and neurodegenerative disorders Keywords: GLP-1, Insulin, Glucagon, Diabetes, Obesity, Incretin 1

These class of drugs are generally considered safe
