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Description
Individuals with certain FTO variants, for example, may show blunted satiety from diet alone but enhanced response to GLP-1 agonism
Increased cytoplasmic Ca +2 triggers mitochondrial ATP generation and insulin exocytosis from insulin granules
10.1210/en.2013-1096 65
Thomas, J., Suarez Arbelaez, M
Patients experiencing this condition may appear older due to sagging skin and reduced facial volume
Across multiple weight-loss interventions, including dietary energy restriction and pharmacologic therapies, a proportion of the total weight loss consists of fat-free mass, including skeletal muscle [3,4]
