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We evaluated ALT-801 in a translational, biopsy-confirmed diet-induced obese (DIO) mouse model of NASH (DIO-NASH) 22 and investigated the effects of a 12 week treatment regimen on metabolic and biochemical parameters, hepatic pathology, and individual changes in NAFLD Activity Score (NAS) and fibrosis stage

However, the weaken effect of semaglutide on expression of MYH7 and ANP was eliminated by HCQ (Fig

Its monthly dosing is a notable differentiator