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Its not uncommon for new medications to cause some initial disruption as your body adjusts

Rodriguez R, Moreno M, Lee AY, Godoy-Lugo JA, Nakano D, Nishiyama A, et al

As a result, that stress and those stress hormones can alter your blood sugar by instigating reactive hypoglycemia (amongst other things)

Millions of people are losing weight faster than their skin can adapt, and the result is a look that feels at odds with how good the rest of the journey is going

Obes Pillars 15:100186 Karakasis P, Patoulias D, Fragakis N, Mantzoros CS (2025) Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: systematic review and network meta-analysis

Meanwhile, about half of people taking phentermine lose at least 5% within three months