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More widespread breast cancer screening and improved treatments have contributed to a more than 40% decline in breast cancer deaths in the past 40 years, said ACR Chief Research Officer Etta D

Even if GLP-1 levels themselves do not rise substantially, the bodys inflammatory or autonomic response may activate GLP-1like pathways, especially along the gut-brain axis

Adverse Effects and Long-Term Safety Concerns While GLP-1 receptor agonists have shown significant benefits, their widespread use is limited by potential side effects such as gastrointestinal distress, pancreatitis risk, and concerns over long-term metabolic effects
8,9,10 Long-term dietary irregularities and metabolic dysfunction caused by obesity have also been demonstrated to increase the prevalence of UC

Any association is more likely related to underlying conditions such as diabetes

In the UK, NHS diabetic eye screening guidance has not required extra screening purely because someone starts a GLP-1 or has rapid improvement, but if someone has missed their last screening and is about to start treatment, they can be re-invited on request