oral glp-1 medication Solution – Affordable Weight Loss Treatment For Overweight Adults Oral GLP-1 for Medical Weight

Viollet, B

doi: 10.1097/DSS.0000000000003802 [DOI] [PMC free article] [PubMed] [Google Scholar] 64

doi: 10.1172/JCI10842 114 da SilvaAAdo CarmoJMLiXWangZMoutonAJHallJE

The available approaches focus on metabolic pathway modifiers (e.g., the Farnesoid X-receptor agonists obeticholic acid and cilofexor, the acetyl-CoA carboxylase inhibitor firsocostat, the PPAR agonist elafibranor) on the one hand, and agents with anti-inflammatory and/or antifibrotic action (e.g., the CCR2/5 inhibitor cenicriviroc and the ASK-1 inhibitor selonsertib) on the other

Serotonin also induces the expression of inflammation factors like tumor necrosis factor and interleukin-6, which can be prevented by the TPH1 inhibitor LP533401

Clinical Therapeutics