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Nature 407 : 908913 Tschop M et al

Extended-release (or time-release) melatonin releases gradually over several hours and may help those who wake up too early or have trouble staying asleep

Research shows patients on semaglutide who prioritize 25-35 grams of protein per meal maintain muscle mass while losing fat, preventing the lean-tissue loss that sometimes accompanies rapid weight decline

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The study of epigenetics for the identification of specific genotypes and phenotypes [192,193] could help determine algorithms and predictive models for personalized decision-making to optimize therapeutic benefit and minimize associated risks [193,194]