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In order to overcome the limited efficacy and short half-life of Ex-4, Chien et al

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There are also less common but important risks including gallbladder disease, pancreatitis, dehydration from vomiting or diarrhea, worsening reflux or gastroparesis symptoms

More detailed body scans in clinical trials show that a fraction of the weight lost (a few percent) is from lean tissue, including muscle

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