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GLP-1 receptor agonists used for the treatment of diabetes, have shown some neuroprotective effects in cellular and animal models of Alzheimers disease (AD) and Parkinsons disease (PD)

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However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

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While Medicare patients initiating treatment on insulin often need additional medications over time, this reflects not only clinical confidence in these newer therapies, but also the growing recognition that they can simplify treatment regimens for patients who might otherwise juggle multiple prescriptions