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100 Berro et al
GLP-1 receptor agonists, such as semaglutide (Wegovy, Ozempic) and tripeptide (Zepbound), are medications designed to mimic the effects of natural GLP-1

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Conclusions While the advent of GLP-1R agonists have indisputably revolutionized the pharmaceutical intervention of obesity, further improvements in efficacy and tolerability are necessary to maximize the long-term health outcomes of patients
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This peptide, which they named 'exendin-4', not only stimulated insulin secretion in the same way as GLP-1 but also had the advantage that it remained active for more than two hours after subcutaneous injection
