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Maintenance Dosing: Once the desired therapeutic effect is achieved, a maintenance dose is established

Mood changes, including irritability, anxiety, or depressive symptoms, affect a small subset of users

This is especially important if you inject in your thigh, since increased blood flow during leg exercise can accelerate absorption and intensify side effects

These doses produce meaningful metabolic effects that require higher semaglutide doses to approximate

The SURMOUNT-2 trial in patients with both obesity and type 2 diabetes showed somewhat lower but still impressive results: 12.8% to 14.7% weight loss over 72 weeks

Cost comparison Semaglutide currently costs approximately $1,350 per month at retail pharmacy prices for the weight management dose