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How do bariatric surgery and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) compare as obesity treatments regarding weight loss, ongoing costs, and health care utilization in a clinical setting

For people who stopped taking GLP-1 weight-loss medications, patients regained about 60% of the weight []

US gut health company Pendulum Therapeutics has introduced Gut Fuel, a doctor-formulated prebiotic fibre and polyphenol powder combining resistant potato starch, baobab, acacia, oat beta-glucan and grape seed extract to support the microbiome, metabolic function and natural GLP-1 pathways

A mitochondrial switch ("SLC25A45") controls whether mitochondria burn fat or carbohydrate, and removing it (in mice) makes GLP-1 drugs stop working for fat loss entirely