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Of participants who discontinued due to side effects, 73% quit during weeks 4 through 12 (the peak period)

The glucagon-like peptide 1 (GLP-1) market has witnessed robust growth, expanding from $22.06 billion in 2025 to an expected $23.88 billion in 2026, at a compound annual growth rate (CAGR) of 8.2%

American Journal of Psychiatry, 158, 405-415

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[DOI] [PMC free article] [PubMed] [Google Scholar] 161.Marker T, Sell H, Zillessen P, Glode A, Kriebel J, Ouwens DM, et al

None of these mechanisms interfere with GLP-1, GIP, or glucagon receptor signaling
