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The in vivo effects of AT-7687 were evaluated in obese cynomolgus monkeys, and when combined with the GLP-1 analogue liraglutide, AT-7687 enhances weight reduction induced by liraglutide and improves glycemic control and lipid metabolism (51)

Alm disso, so recomendados como escolha preferencial em indivduos com doena cardiovascular aterosclertica, insuficincia cardaca ou doena renal crnica, dada sua capacidade de reduzir eventos cardiovasculares e retardar a progresso da doena renal (ELSAYED et al., 2023)
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