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Serious adverse events were slightly higher with Zepbound (4.8%) than Wegovy (3.5%), but discontinuation rates due to side effects were identical (6 patients in each group)

For the treatment of obesity, GLP-1RAs and GIP/ GLP-1RAs are indicated in patients with a body mass index (BMI) 30 kg m 2 , or 27 kg m 2 in the presence of at least one weight-related comorbidity, to support weight reduction [23]

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And the drugs side effects, like stomach upset, may also need professional support as sometimes the dosage may need adjustment, said Sheer, also a UF College of Medicine professor who is the program director for the Obesity Medicine Fellowship at UF Health

doi: 10.1111/j.1742-1241.2011.02656.x