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In addition, we tested for co-localization with expression quantitative trait loci in the locus, and identified none that colocalized with the GWAS signal (Supplementary Information)

10.2967/jnumed.106.038679

More recently, there have been studies into repurposing drugs for Alzheimer's Disease, which is a form of neurodegeneration or dementia

Additionally, a longer course of 26 weeks Efinopegdutide (5.0, 7.4 or 10.0 mg) treatment in non-diabetic obese patients demonstrates significant placebo-corrected body weight reductions of 6.7%, 8.1%, and - 10.0%, relative to 5.8% of the active comparator Liraglutide (3 mg) [4]

Our Inflammation and Longevity Medicine hub and article on Inflammation, Brain Health, and Mental Wellbeing explain why inflammatory burden belongs in the cognitive-health conversation

The primary side effects of liraglutide are gastrointestinal, including nausea, diarrhea, constipation, and vomiting, mitigated by gradual dose escalation