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GLP-1 is having a cultural momentbut it's been quietly shaping metabolic health research for decades

Conclusions Dose levels of bimagrumab administered weekly subcutaneously resulted in PK profiles and PD effects comparable with monthly intravenous dosing, which supports the feasibility of the subcutaneous route of administration for bimagrumab for future clinical development.

The GLP-1RA group had greater weight loss during the weight maintenance period (2.3kg (95% CI=0.6 to 4.0)), and had fewer meal replacements per day compared with the control group (minus one meal per day (95% CI=0.6 to 1)), P<0.001

It should be used together with diet and exercise

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