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It works by blocking 2 calcium channels and inhibiting the release of excitatory neurotransmitters from presynaptic vesicles

Eating smaller amounts more often is easier on the stomach

In another case report, a 50-year-old female patient with type II diabetes, abdominal obesity, and psoriasis received a 10-month treatment with semaglutide, which led to a significant reduction in body weight

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GLP-1 signaling activates protein kinase A (PKA) and Epac2 , supporting -cell survival and insulin gene expression

It can also make other side effects more likely, such as nausea or vomiting, so its best to avoid alcohol after you first start taking Wegovy or after a dose increase