Semaglutide –
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Comparative effects of intragastric and intraduodenal administration of quinine on the plasma glucose response to a mixed-nutrient drink in healthy men: relations with glucoregulatory hormones and gastric emptying
They share reward circuitry, particularly the dopamine pathways that decide what the brain codes as worth pursuing
Al-Qallaf and Das, 2009)
For most patients, GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) require long-term use to maintain their benefits
The best spot is the lower abdominal area, roughly between the hip bones and two inches below the navel
