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The patient was a 44-year-old male with severe morbid obesity, heart failure, oxygen-dependent obesity hypoventilation syndrome, uncontrolled hypertension, anemia, and depression

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Body weight and composition, subjective feelings of appetite and appetite-related hormones (insulin, active ghrelin (AG), active GLP-1, total PYY and CCK) were measured in fasting and postprandially, at baseline, on day 3 of the diet, 5 and 10% WL, and at wks 9 and 13