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Description
Methods Retrospective study utilizing data from a federated research network (TriNetX)
Based on a systematic synthesis of available findings, we conclude that there is considerable support for the neuromodulatory potential of gut-based circulating peptides on reward responses
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By exploring human studies and mechanistic insights, this review underscores irisins potential to address global health challenges, such as obesity and type 2 diabetes, while advancing strategies for personalized exercise interventions.
Some studies showed equivalentor even lowertotal weight loss at one year compared to surgery alone
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