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Enzymatic production of xylooligosaccharides from brown coconut husk treated with sodium hydroxide

En las ratas obesas prediabticas OLETF (Otsuka-Long-Evans-Tokushima Fatty rats) se observ que despus de 12 semanas de tratamiento con la liraglutida exista una adecuada conservacin de la morfologa de los islotes pancreticos, regulacin a la alta de la expresin de factor antiapopttico Bcl-2 y regulacin a la baja de la expresin del factor proapopttico Bax, resultados que sugieren que la liraglutida tiene un papel protector en la formacin y la funcin del islote pancretico mediante el control de las vas apoptticas, lo que permite mantener la funcin endocrina de la clula beta y prevenir las alteraciones de la glucosa y la aparicin de DM244

While GLP-1R agonists have demonstrated cardiovascular benefits in clinical trials, including reduced rates of major adverse cardiovascular events (MACE) in T2DM patients, their antithrombotic efficacy is generally considered less potent than that of traditional antithrombotic agents

Most of the time this reflects the positive inotropic effect (stronger contractions) rather than any dangerous rhythm abnormality

Previous clinical and preclinical studies have been contradictory, says co-corresponding author Yonggui Yuan of Southeast University in Jiangsu, China