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A small lump or nodule at the injection site can also occur

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Each step-up occurs every four weeks, moving from 0.25 mg 0.5 mg 1.0 mg 1.7 mg 2.4 mg at maximum

however, it is advisable to include thyroid function tests in the routine screening of diabetic patients, particularly those treated with GLP-1 Ras, with the goal of optimizing patient care and management

Because retatrutide lowers blood glucose through multiple hormonal pathways, combining it with insulin or sulfonylureas (such as gliclazide or glibenclamide) may substantially increase the risk of hypoglycaemia