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G., Bortolato, A., Blaney, F

Global assessment of the evidence The Modified Bradford Hill Criteria was used to assess the potential relationships among various available evidence [33,34,35]
[DOI] [PubMed] [Google Scholar] 253.Bhawra J, Kirkpatrick SI, Hall MG, Vanderlee L, White CM, Hammond D

GIP (glucose-dependent insulinotropic peptide) and GLP-1 (glucagon-like peptide-1) are released by cells at the beginning of the intestines in response to food
Therefore, to propose the opposite and suggest that glucagon agonism should be included in the pharmacotherapy of obesity and type 2 seems paradoxical

Retatrutide might lead to more stomach trouble because of higher doses, but the long-term data are not definitive yet
