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A total of 296 participants without a history of significant alcohol consumption were randomly assigned to active treatment

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Kadowaki T, Chin R, Ozeki A, Imaoka T, Ogawa Y (2022) Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): a multicentre, randomised, open-label, parallel-group, phase 3 trial

Even among obese patients, a modest weight loss of 5% of their body weight can dramatically improve health outcomes in various categories, and Zepbounds results are significantly more profound, potentially improving health outcomes even further

The prevalence is expected to rise dramatically, with projections indicating 783 million people will have diabetes by 2045 [4]
