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These medications are mixed or adjusted to meet a patients specific needs and have more variability in effectiveness

The first two to six weeks: Your body is shifting how it processes food and glucose

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On average, patients experience a reduction in appetite once the medication is started, says Kushner

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Thus, the autonomic nervous system, in particular the vagus nerve (which innervates a significant portion of the gut), is thought to play a role in this early phase of release, with nutrient content being more important for the second phase (85)