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Mounjaro, however, contains tirzepatide, which has a dual action, binding to both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, enhancing its effects on weight loss and blood sugar control

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[DOI] [PubMed] [Google Scholar] 65.Mller TD, et al

The outcomes of the DAPA-HF trial13,14 showed promise in patients without diabetes, resulting in dapagliflozin receiving approval from the Food and Drug Administration (FDA) to be used as an adjunct agent (already on guideline-directed medical therapy) in heart failure patients with reduced ejection fraction in preventing hospitalization