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They present a framework to guide research and development teams based on the five most important technical determinants of project success and pipeline quality: the right target, the right patient, the right tissue, the right safety and the right commercial potential

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Conclusions BMS is a pivotal therapeutic intervention for patients with obesity and OSA, offering major respiratory and metabolic advantages.Nonetheless, the persistence of OSA in a considerable proportion of patients underscores the necessity for multidisciplinary, long-term management
