new glp 1 study shows popular GLP-1 weight loss drug may slow biological aging New Study Reveals Genetic Predictors

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For example, exendin-based GLP-1 analogues have an alanine to glutamic acid substitution in the second position [40]

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Nowowiejska J, Baran A, Flisiak I

While GIP has lost most of its insulinotropic activity in patients with T2D, GLP-1 has retained enough of its insulinotropic activity to stimulate insulin secretory responses even in patients with T2D [55]